The Science Behind MIOLO
What the MIOLO formula is, how patient data is protected, and how to license the engine behind it.
Written for surgeons, hospital teams, ophthalmic societies and IOL manufacturers evaluating the platform.
MIOLO is an original IOL formula built with machine learning. Its accuracy is equal to or better than the latest generation of IOL formulas.
MIOLO results have been checked in more than 20,000 calculations across virgin, short, post-LASIK, post-RK and keratoconus eyes, with accuracy equal to or better than the latest generation.
The Platform at a Glance
| What it is | A professional suite of seven IOL power calculators for cataract surgery, free to use at miolo.ai. |
|---|---|
| Formula | An original formula built with machine learning, the MLF (Machine Learning Factor), with accuracy equal to or better than the latest generation of IOL formulas. |
| Clinical coverage | Routine eyes, short eyes, toric planning, post-LASIK and post-PRK, keratoconus, post-radial keratotomy, sulcus implantation after posterior capsule rupture, supplementary add-on IOL in pseudophakic eyes, and post-operative toric diagnosis. |
| Privacy | Patient identity never leaves the surgeon's device. Servers receive only anonymized clinical data. Personal data protection enforced by architecture. |
| Author | Bruno Miolo, MD, M.Sc.: practicing cataract surgeon, scientist and AI engineer. |
| Cost | Free for surgeons. No ads, no data resale. |
| Licensing | The engine runs server-side behind a closed API and is available for licensing: IOL manufacturers, ophthalmic societies, hospital groups, clinics and white-label deployments. |
Principles
The MLF (Machine Learning Factor)
MIOLO is an original IOL formula built with machine learning. Its accuracy is equal to or better than the latest generation of IOL formulas.
Determinism where it matters
Given the same biometry, the engine returns the same answer, every time, on every device. There is no generative step anywhere in the clinical path.
One author, full accountability
The engine is designed, built and audited by the same surgeon who uses it in the operating room. Every formula decision has a name attached to it, and every publication declares its conflicts of interest.
One Engine, Seven Instruments
Every calculator on the platform runs on the same engineering discipline. All of them are free to use.
Spherical IOL power for routine and atypical eyes.
Toric IOL power, cylinder and axis, with mandatory surgically induced astigmatism input.
IOL power after myopic or hyperopic LASIK/PRK, in keratoconus and after radial keratotomy.
IOL power adjustment for ciliary sulcus implantation after posterior capsule rupture, with optic capture support.
Supplementary (add-on / piggyback) IOL power for pseudophakic eyes with a stable primary lens in the bag, calculated from the current residual refraction. Catalog-locked to the manufacturers' published ranges and step sizes by family: Rayner Sulcoflex (Aspheric, Toric, Trifocal) and 1stQ AddOn (Refractive, Toric, Trifocal, Trifocal Toric, EDOF).
Post-operative toric IOL analysis: the axis of minimum residual astigmatism and the expected residual at the current and at the calculated axis. The decision belongs to the surgeon.
Back-calculation of the astigmatic state of a pseudophakic eye from the manifest refraction.
Privacy by Architecture
The public calculators process biometry in real time and store nothing. The optional Surgeon Area keeps patient identity in an encrypted vault inside the surgeon's own browser; our servers receive only anonymized clinical data. Patient-identifying information never leaves the device.
Personal data protection is enforced by the architecture itself, not by a policy promise. Details in the Privacy Policy.
Technical Publications
The reasoning behind the platform is documented in technical articles with Vancouver-style references verified against PubMed. Conflicts of interest are declared in every publication.
Which keratometry belongs in a toric calculator after LASIK or PRK, the evidence on predicted versus measured posterior corneal astigmatism, and the double-counting error.
The physics of error amplification, the evidence from recent meta-analyses and practical recommendations by axial length.
Why formulas fail in ectatic corneas and what the evidence recommends for cataract surgery in keratoconus.
How clinically trained algorithms are changing medical specialties, with ophthalmology at the center.
The vector mathematics of SIA and why every surgeon should measure their own.
The limits of traditional formulas and the case for data-driven calculation.
Authorship
MIOLO is developed by Bruno Miolo, MD, M.Sc: a practicing cataract surgeon, a scientist and an AI engineer in the same person.
The tools are shaped in live surgical practice, because each calculator exists to answer something a real operating room demanded, and they are built and audited by the same hands that operate. That combination of clinic, science and engineering is what the platform is made of.
Frequently Asked Questions
What is MIOLO.AI?
MIOLO.AI is a free, professional-grade suite of intraocular lens power calculators for cataract surgery. It covers standard, toric, post-refractive (post-LASIK, post-PRK, keratoconus, post-RK), sulcus calculation after posterior capsule rupture and supplementary add-on IOL calculation in pseudophakic eyes, plus post-operative toric IOL diagnosis.
Is MIOLO free to use?
Yes. Every calculator on the platform is free for surgeons, with no ads and no resale of data. Creating an account is optional and adds conveniences such as saved calculations, favorite lenses and a personal SIA database.
How accurate are the MIOLO calculators?
MIOLO is an original IOL formula built with machine learning, and its accuracy is equal to or better than the latest generation of IOL formulas.
What makes MIOLO different from other IOL calculators?
Three things: an original machine learning formula with accuracy equal to or better than the latest generation of IOL formulas; privacy enforced by architecture, with patient identity never leaving the device; and a single accountable author, a practicing cataract surgeon who is also the engineer of the platform.
Who is behind MIOLO.AI?
Bruno Miolo, MD, M.Sc., a practicing cataract surgeon, scientist and AI engineer. He designs, builds and audits the calculation engine personally, and the tools are shaped by what his own operating room demands.
Is patient data safe on MIOLO.AI?
The public calculators process biometry in real time and store nothing. In the optional Surgeon Area, patient identity is kept in an encrypted vault inside the surgeon's own browser and never reaches the servers, which receive only anonymized clinical data. Personal data protection is enforced by this architecture.
Can companies license the MIOLO engine?
Yes. The calculation engine runs server-side behind a closed API and is available for licensing and integration: lens-specific calculators and constant optimization for IOL manufacturers, member tools for ophthalmic societies, EMR and biometer integration for hospital groups and clinics, and white-label deployments. Licensing inquiries: [email protected].
Which difficult eyes does MIOLO cover?
Short eyes, post-LASIK and post-PRK eyes (myopic and hyperopic), keratoconus, post-radial keratotomy, and sulcus implantation after posterior capsule rupture with or without optic capture.
Licensing and Partnerships
The MIOLO calculation engine runs server-side behind a closed API, which makes it straightforward to license and integrate without exposing the proprietary models. Typical arrangements include:
- IOL manufacturers: lens-specific calculators and constant optimization for new and existing platforms.
- Ophthalmic societies: calculation tools offered as a member benefit.
- Hospital groups and clinics: EMR and biometer integration through the API.
- White-label deployments: the engine behind your brand.
Licensing inquiries: [email protected]
Judge the engine by its answers
Run your own cases, including the difficult ones, and compare the results with the formulas you already trust.
Open the calculators